IngredientEvidence: A — Strong RCT evidence
✓ Editor triedZinc Oxide / Mineral SPF
Love It
No member score yet
“Do I really need to say anything here?
If you are someone on the platform, you got to be someone who uses sunscreen religiously, else, what's the point of even being here?”
For: PIH (Post-Inflammatory Hyperpigmentation) · Sun Damage & Dark Spots · Rosacea & Redness
IngredientEvidence: C — Emerging evidence
✓ Editor triedBiomimetic & Multi-Peptide Complexes
Worth Exploring
No member score yet
“I have used several toners and serums, there is always one in rotation however nothing much to report here, I don't see any major effects of it. In short, you don't need it. I just use it as a toner format, doesn't hurt :)”
For: Fine Lines & Wrinkles · Loss of Firmness & Elasticity · Crepey & Thinning Skin
IngredientEvidence: B — Moderate evidence
✓ Editor triedHyaluronic Acid
Not For Me
No member score yet
“So here's the thing. In most of the serums and products that you use, hyaluronic acid is always a part of the base formulation. So getting it separately as a product does not make sense to me at all. What I would recommend is that you buy products that already contain hyaluronic acid. It's good for a bit of a plumping and moisturization effect, but it is not a product you buy on its own.”
For: Damaged Skin Barrier · Dehydrated Skin
IngredientEvidence: B — Moderate evidence
✓ Editor triedFerulic Acid
Not For Me
No member score yet
“Perhaps it was the format, but I didn't love it. As a combination with C+E it's suppose to be outstanding, but I didn't see it as a game-changer. Might try it out again, and report back.”
For: PIH (Post-Inflammatory Hyperpigmentation) · Sun Damage & Dark Spots · Dullness & Uneven Tone
IngredientEvidence: B — Moderate evidence
✓ Editor triedMandelic Acid
Not For Me
No member score yet
“Exfoliant newbies... this is where you start!”
For: PIH (Post-Inflammatory Hyperpigmentation) · Acne (Comedonal & Cystic) · Rough Skin Texture
IngredientEvidence: B — Moderate evidence
✓ Editor triedRosehip Oil
Worth Exploring
No member score yet
“There are days where I take a break on all of the ingredients that I use, and then I have a very nice mix of oils. One of the oils that I do like to add is rosehip oil. It's very gentle. It's very calming. If you're someone who takes a couple of days off every month similar to how I do, then it could be something that you add to your concoction. Don't expect some drastic results, but more of gentle hydrations and calming.”
For: PIH (Post-Inflammatory Hyperpigmentation) · Acne (Comedonal & Cystic) · Acne Scarring & Pitting
IngredientEvidence: C — Emerging evidence
✓ Editor triedCollagen (Topical)
Not For Me
No member score yet
“Similar to PDRN, there is a lot of hype around moisturizers and serums which have collagen in it. Again, collagen is a large molecule. It does not absorb directly into your skin when applied to the face. The best form of it is to take it orally with a powder format or a gummy or supplement, but it's not something that would make a huge difference other than hydration and plumping when applied topically.”
For: Fine Lines & Wrinkles · Dehydrated Skin · Neck & Décolleté Aging
IngredientEvidence: B — Moderate evidence
✓ Editor triedBakuchiol
Not For Me
No member score yet
“Not for me, but if you are scared of jumping on to retinols, this is where you can start however this won't do much, just maybe get you comfortable with the idea of retinols.”
For: Fine Lines & Wrinkles · Loss of Firmness & Elasticity
IngredientEvidence: B — Moderate evidence
✓ Editor triedTranexamic Acid (TXA)
Love It
No member score yet
“Part of my niacinamide serum - always part of my morning routine.”
For: PIH (Post-Inflammatory Hyperpigmentation) · Melasma · Dark Circles & Under-Eye
IngredientEvidence: C — Emerging evidence
✓ Editor triedCaffeine
Not For Me
No member score yet
“So the only form of caffeine I use in my skin care is in under eye patches, which contain caffeine, which are supposedly good for under eye darkness. I don't see any dramatic effect to be fair, but it's there as a mix of ingredients so I continue to use it. Not something that I would go and purposefully buy on its own.”
For: Dark Circles & Under-Eye
IngredientEvidence: A — Strong RCT evidence
✓ Editor triedGlycolic Acid
Love It
No member score yet
“Glycolic acid has multitudes of benefits. It's amazing to use on your skin, especially if you have KP or you have marks and pigmentation or you have bumpy rough skin. I use it on my body. I use it on my face. The easiest format though it toner pads or peeling pads with glycolic acid for the face, and liquid form in spray bottle for the body.”
For: Dullness & Uneven Tone · Acne (Comedonal & Cystic) · Acne Scarring & Pitting
IngredientEvidence: C — Emerging evidence
✓ Editor triedResveratrol
Not For Me
No member score yet
“I have tried it in a couple of serums. However, I don't think it was a game changer nor something significant enough to see much results. So I'm not very keen on it. I've not seen yet a lot of data backing it up either. This is not something you need to spend money on yet.”
For: Sun Damage & Dark Spots · Dullness & Uneven Tone · Fine Lines & Wrinkles
IngredientEvidence: A — Strong RCT evidence
✓ Editor triedCeramides, Cholesterol & Fatty Acids
Love It
No member score yet
“Ceramides specifically is what I look for in my moisturizers, specially for my morning routine, this I found to be the best ingredient fit for barrier protection and AM routine.”
For: Damaged Skin Barrier · Rosacea & Redness · Dehydrated Skin
IngredientEvidence: A — Strong RCT evidence
✓ Editor triedVitamin C (L-Ascorbic Acid)
Love It
No member score yet
“Yes, absolutely! This is one of your basic skincare must. Do yourself a favor and start using it!”
For: PIH (Post-Inflammatory Hyperpigmentation) · Sun Damage & Dark Spots · Dullness & Uneven Tone
IngredientEvidence: A — Strong RCT evidence
✓ Editor triedPanthenol (Pro-Vitamin B5)
Love It
No member score yet
“I actually use this as the very last step on days when I do microneedling, have done a peel or have been a bit rash with experimenting with ingredients. You will find some products specifically formulated as thick creams out of this, slather a layer on when you go to bed, you will wake up with a hydrated, calm, glowy skin the next morning!”
For: Damaged Skin Barrier · Rosacea & Redness · Dehydrated Skin
IngredientEvidence: B — Moderate evidence
✓ Editor triedPDRN (Polydeoxyribonucleotide)
Worth Exploring
No member score yet
“So this one I really want to talk about because there is way too much hype and drama around this ingredient, and the reality is that the molecules are too big for it to be applied topically and absorbed in your skin. It's an excellent form of hydration and plumping effect, but it has no long term benefits when topically applied. However, as an injectable, it's an excellent product if you're willing to accept the cost for a benefit for a three to four months because that's how long the effects would last for your face.”
For: Acne (Comedonal & Cystic) · Acne Scarring & Pitting · Fine Lines & Wrinkles
IngredientEvidence: C — Emerging evidence
✓ Editor triedGlutathione
Not For Me
No member score yet
“Other than a glowy effect toner, it's all just marketing.”
For: PIH (Post-Inflammatory Hyperpigmentation) · Dullness & Uneven Tone
IngredientEvidence: B — Moderate evidence
✓ Editor triedPeptides (Overview)
Worth Exploring
No member score yet
No personal note logged yet — see the full research and evidence breakdown on the detail page.
For: Fine Lines & Wrinkles · Loss of Firmness & Elasticity · Crepey & Thinning Skin
IngredientEvidence: B — Moderate evidence
✓ Editor triedCollagen (Oral / Ingestible)
Love It
No member score yet
“Love Love Love!
I started taking collagen powder in my morning tea, I did notice my skin feeling fresher and plumper after some time, there is no harm in trying this one, you might get hooked to it as well!”
For: Fine Lines & Wrinkles · Loss of Firmness & Elasticity · Crepey & Thinning Skin
IngredientEvidence: B — Moderate evidence
✓ Editor triedPHAs — Gluconolactone & Lactobionic Acid
Worth Exploring
No member score yet
No personal note logged yet — see the full research and evidence breakdown on the detail page.
For: Damaged Skin Barrier · Rough Skin Texture
IngredientEvidence: B — Moderate evidence
✓ Editor triedHypochlorous Acid (HOCl)
Love It
No member score yet
“I love it, specially for gym rats... sweating in a closed gym with germs around you, and if you like sauna after, you absolutely need this. Also super if you are out all day or at work, and prone to breakouts, having a spray bottle in your bag is worth it. freshens you up and kills all the germs that around about to give you acne!”
For: Acne (Comedonal & Cystic) · Damaged Skin Barrier · Rosacea & Redness
IngredientEvidence: A — Strong RCT evidence
✓ Editor triedAdapalene
Not For Me
No member score yet
“Too, too gentle for me! To be clear, this isn't a knock on the evidence - adapalene has some of the strongest acne data of any retinoid, and it's a legitimately good, well-tolerated option for a lot of people. It just wasn't enough for what my skin needed at the time; I wanted a stronger effect than adapalene alone was giving me. "Not For Me" here is about fit, not about whether it works.”
For: PIH (Post-Inflammatory Hyperpigmentation) · Acne (Comedonal & Cystic) · Fine Lines & Wrinkles
IngredientEvidence: B — Moderate evidence
✓ Editor triedCentella Asiatica / Madecassoside (Cica)
Not For Me
No member score yet
“I already use a few other ingredients for skin barrier protection, but I did start off with this one first, really liked how gentle and calming it was for my skin. Worth exploring if your barrier needs help.”
For: Acne (Comedonal & Cystic) · Acne Scarring & Pitting · Damaged Skin Barrier
IngredientEvidence: B — Moderate evidence
✓ Editor triedRetinal (Retinaldehyde)
Not For Me
No member score yet
“Slow release, moderate strength format, this is worth moving to, after you have tried adapalene or bakuchiol formats.”
For: PIH (Post-Inflammatory Hyperpigmentation) · Acne (Comedonal & Cystic) · Fine Lines & Wrinkles
IngredientEvidence: B — Moderate evidence
✓ Editor triedRetinol
Not For Me
No member score yet
“Strong clinical evidence. If tretinoin is not accessible, retinol is the most evidence-backed OTC alternative for skin renewal and pigmentation.”
For: PIH (Post-Inflammatory Hyperpigmentation) · Acne (Comedonal & Cystic) · Fine Lines & Wrinkles
IngredientEvidence: A — Strong RCT evidence
✓ Editor triedSalicylic Acid
Love It
No member score yet
“I love it in my bodywashes and water based cleansers, I am very prone to comedones and I really think this helps, gentle enough for daily use, however make sure you are strict with you sunscreen.”
For: Acne (Comedonal & Cystic) · Enlarged Pores · Hormonal Acne
IngredientEvidence: B — Moderate evidence
✓ Editor triedSnail Mucin (SCSM)
Not For Me
No member score yet
“Perhaps knowing it's a SNAIL mucin or just that it wasn't a game changer - I simply did not like this one, I don't like the texture, I don't like how it sits on my skin, and didn't give me a significant result. Not something I will use again.”
For: Acne (Comedonal & Cystic) · Acne Scarring & Pitting · Damaged Skin Barrier
IngredientEvidence: B — Moderate evidence
✓ Editor triedGHK-Cu (Copper Peptides)
Worth Exploring
No member score yet
“Okay, to be honest - I just started using in a serum format, 1%. I can't say there is much change with it yet, but I will report back after a month. And no, I won't inject it ever!
If you want the fuller picture on why a copper peptide serum and a copper peptide injection are not remotely the same risk, I wrote about it on The Edit: "Copper Peptides Are Trending Again. A Serum and an Injection Are Not the Same Risk."”
For: Acne (Comedonal & Cystic) · Acne Scarring & Pitting · Fine Lines & Wrinkles
IngredientEvidence: A — Strong RCT evidence
✓ Editor triedAzelaic Acid
Love It
No member score yet
“Dual-action for pigmentation and acne. Took 6 weeks to see real change — but the results held. Also calmed redness consistently. It enters my skin care when I have been too adventurous with my experiments, and I add this as part of my PM routine with tretinoin.”
For: PIH (Post-Inflammatory Hyperpigmentation) · Melasma · Acne (Comedonal & Cystic)
IngredientEvidence: B — Moderate evidence
✓ Editor triedAlpha Arbutin
Not For Me
No member score yet
No personal note logged yet — see the full research and evidence breakdown on the detail page.
For: PIH (Post-Inflammatory Hyperpigmentation) · Melasma · Sun Damage & Dark Spots
IngredientEvidence: B — Moderate evidence
✓ Editor triedKojic Acid
Not For Me
No member score yet
No personal note logged yet — see the full research and evidence breakdown on the detail page.
For: PIH (Post-Inflammatory Hyperpigmentation) · Melasma
IngredientEvidence: A — Strong RCT evidence
✓ Editor triedTretinoin
Love It
No member score yet
“Love, Love, Love.
This was a game changer, took me a couple of years to actually move to this. My only regret - why I didn't start sooner! I have had the best skin upgrade with this one. Takes a WHILE to get used to it, but I promise you, absolutely worth it.
Only disclaimer: this is real prescription strength, not a starter retinoid. What matters is tolerance and indication, not a birthday - if you haven't built tolerance with an OTC retinol or retinal first, or you don't have a specific concern this is actually treating, it's not the one to reach for yet, regardless of age. Go in through a dermatologist so it's matched to what your skin actually needs.”
For: PIH (Post-Inflammatory Hyperpigmentation) · Acne (Comedonal & Cystic) · Fine Lines & Wrinkles
IngredientEvidence: B — Moderate evidence
✓ Editor triedLactic Acid
Not For Me
No member score yet
“I usually use it as form of lotions, it is definitely gentler than glycolic acid, so great for people just starting off with exfoliants. For me, glycolic is the GOAT.”
For: Rough Skin Texture · Dehydrated Skin · Damaged Skin Barrier
IngredientEvidence: C — Emerging evidence
✓ Editor triedAstaxanthin
Worth Exploring
No member score yet
“I have been taking it as an oral medication for a while now. I wouldn't say I have seen dramatic results but based on emerging data, I rather keep it in my supplement stack!”
For: Sun Damage & Dark Spots · Dullness & Uneven Tone · Fine Lines & Wrinkles
IngredientEvidence: B — Moderate evidence
✓ Editor triedArgireline (Acetyl Hexapeptide-3)
Worth Exploring
No member score yet
“Tried multiple times, for someone who loves botox since experimenting it last year - I rather get botox. But if you are not going in that direction, this might be worth it for you.”
For: Fine Lines & Wrinkles
IngredientEvidence: A — Strong RCT evidence
✓ Editor triedNiacinamide
Love It
No member score yet
“My most consistent active. Visible PIH improvement within 8 weeks. Works best layered under SPF in the morning routine.”
For: PIH (Post-Inflammatory Hyperpigmentation) · Dullness & Uneven Tone · Acne (Comedonal & Cystic)
IngredientEvidence: A — Strong RCT evidence
✓ Editor triedUrea
Love It
No member score yet
“Love it for body, rough knees, elbows and feet.. not going to put that on my face though! :)”
For: Damaged Skin Barrier · Rough Skin Texture · Dehydrated Skin
IngredientEvidence: B — Moderate evidence
✓ Editor triedMatrixyl (Palmitoyl Pentapeptide-4)
Worth Exploring
No member score yet
“Tried, but I didn't see major shift - but keep in mind, I also have other modalities that help maintain my skin, so topicals won't give me dramatic changes in terms of anti aging. I would love to hear other people's feedback on this one!”
For: Fine Lines & Wrinkles · Loss of Firmness & Elasticity · Neck & Décolleté Aging
IngredientEvidence: B — Moderate evidence
✓ Editor triedVitamin E (Tocopherol)
Worth Exploring
No member score yet
“Part of the oil concoction I use where I take a break from all the chemicals. No drastic results, but more for calming your skin down and helping it heal.”
For: Sun Damage & Dark Spots · Dullness & Uneven Tone · Damaged Skin Barrier
TreatmentEvidence: B — Moderate evidence
✓ Editor triedMorpheus8
Approach With Caution
No member score yet
“I need to be very clear: I am talking about Morpheus8/RF microneedling here, not regular microneedling. I did three sessions on my face and neck in 2023 and felt I lost facial fat, especially in my cheeks. It took me forever to recover from that, and I did not feel the tightening result justified the damage. I would never do it again on my face. On my belly, it was a different story. I did three sessions there, and because fat loss on the belly was not a concern, I felt the skin elasticity improved.”
For: Loss of Firmness & Elasticity · Acne Scarring & Pitting · Crepey & Thinning Skin
TreatmentEvidence: A — Strong RCT evidence
✓ Editor triedClarity Laser Hair Removal
Love It
No member score yet
“It took me ages to realize I could simplify my life with laser hair removal. I did full body once a month for almost a year, and it was absolutely worth it. Each session took under an hour, and six months after stopping I only have a few tiny scattered hairs here and there. I may do a few maintenance sessions around the one-year mark. Shaving is not the way for me because it causes ingrowns, and waxing is too painful. Laser just made life easier.”
TreatmentEvidence: C — Emerging evidence
✓ Editor triedClear + Brilliant
Love It
No member score yet
“I did Clear + Brilliant in 2024 on my full face and neck because I wanted to improve pores, dullness and that dead-skin layer feeling. It was amazing once I got through the downtime. You come out with genuinely fresh, baby-looking skin. But you need to plan for it properly: avoid the sun like it is the plague, sit at home if needed, and do not underestimate the healing stage because it does not look pretty for a while. I would do it again, but as an annual resurfacing moment, not every month.”
For: Dullness & Uneven Tone · Fine Lines & Wrinkles · Rough Skin Texture
TreatmentEvidence: A — Strong RCT evidence
✓ Editor triedHA Dermal Fillers
Approach With Caution
No member score yet
“I used Juvederm only, and I kept everything extremely conservative: lips 0.3ml, chin about 0.6ml (not a full 1ml), temples 1ml, and a trace amount under the eyes (0.1-0.2ml) using leftover product. Cheek support was not a separate purchase - it came from leftover product from the chin syringe. The best result for me was chin filler because it gave my face more shape without looking obvious. Nothing migrated and I never felt overfilled, but that is because I was strict about not going crazy. The problem is that it did not last well on me; six to twelve months later, my dermatologist said most of it had metabolized. I do not plan to keep doing fillers, except maybe temples if I ever really need it, because I think there are other treatments that support skin without leaving filler in the face.”
For: Facial Volume Loss · Dark Circles & Under-Eye · Fine Lines & Wrinkles
TreatmentEvidence: B — Moderate evidence
✓ Editor triedJalupro
Not For Me
No member score yet
“I tried Jalupro once on my full face while traveling. It was more for a freshened-up look than a serious skin concern. I did notice a glow around the two-to-three-week mark, but it is not something I feel I need again. If you have an event or you feel very dull, it can be worth considering. But for me, good skincare can do a lot of the same work without turning it into another recurring injectable.”
For: Fine Lines & Wrinkles · Dehydrated Skin · Dullness & Uneven Tone
TreatmentEvidence: B — Moderate evidence
✓ Editor triedHydraFacial
Not For Me
No member score yet
“I have done HydraFacial two or three times. Right after, the result is amazing: your face feels fresh and glowing. But it is still a facial. You can do a decent version of the concept at home with a steamer, exfoliant, good cleanser and skincare after. I think it is good before an event or when traveling and wanting to look fresh, but I do not see it as a long-term skin result.”
For: Dehydrated Skin · Dullness & Uneven Tone · Enlarged Pores
TreatmentEvidence: B — Moderate evidence
✓ Editor triedLED Light Therapy
Love It
No member score yet
“LED has been part of my routine for about three years. I have a mask and a lamp, but I usually use the lamp because it is more convenient. I use red light with near-infrared three to four times a week for 15 to 20 minutes. It is not an instant transformation, but I do think it helps maintain my skin quality and glow. My rule is clean skin only: no actives, no acne creams underneath. One night after microneedling, I left the lamp on and fell asleep, so I was exposed to it for far longer than intended. I noticed temporary darkening the next morning, which faded within about a day. That was a one-off from accidental overnight exposure, not something that happens with normal 15-20 minute sessions.”
For: Rosacea & Redness · Acne (Comedonal & Cystic) · Damaged Skin Barrier
TreatmentEvidence: B — Moderate evidence
✓ Editor triedMicroneedling
Love It
No member score yet
“This entry is based on my own hands-on expertise, not general instruction. I've been doing regular microneedling — not Morpheus8 — with a Dr. Pen at home every four weeks for about a year to a year and a half, on my full face and neck, and it has drastically improved my skin quality: I see post-inflammatory marks, pigmentation and acne scars fade over time, usually noticing improvement in under a week. I do not recommend at-home microneedling for beginners. I'm comfortable doing this myself specifically because I've built up years of trial and error, clinic experience watching professionals work, and strict aftercare discipline — not because it's inherently low-risk. My routine: avoid sun, wear sunscreen, avoid harsh actives for about three days, and time it before a weekend at home so I'm not exposed. If you don't have that background, a professional treatment is the safer starting point.”
For: Acne Scarring & Pitting · Rough Skin Texture · PIH (Post-Inflammatory Hyperpigmentation)
TreatmentEvidence: B — Moderate evidence
✓ Editor triedPRP Facial
Worth Exploring
No member score yet
“I have done PRP facial a couple of times, both as injections and with microneedling. It gives a nice glow and a freshened-up look, but for me it is temporary - maybe two to three months at best. If you are doing in-office microneedling, adding PRP is worth exploring because it can help healing and glow. But because I can do regular microneedling at home, I do not see enough benefit in paying triple just to add PRP. And again, I do not recommend at-home microneedling if you have no experience.”
For: Acne Scarring & Pitting · Fine Lines & Wrinkles · Rough Skin Texture
TreatmentEvidence: B — Moderate evidence
✓ Editor triedRF Skin Tightening
Approach With Caution
No member score yet
“Moxie has not personally tried non-needle RF skin tightening; this stays research-only and device-specific until direct experience or verified community feedback exists.”
For: Loss of Firmness & Elasticity · Crepey & Thinning Skin · Fine Lines & Wrinkles
TreatmentEvidence: B — Moderate evidence
✓ Editor triedSofwave
Not For Me
No member score yet
“I tried Sofwave in 2025 after doing Ultherapy the year before. It felt like the gentler cousin: less scary in terms of affecting facial fat, but also more muted in result. I did it for lifting and laxity, but honestly I did not see much difference. Some people say Sofwave works better for them, so this is personal. For me, I would not repeat it.”
For: Loss of Firmness & Elasticity · Fine Lines & Wrinkles · Neck & Décolleté Aging
TreatmentEvidence: C — Emerging evidence
✓ Editor triedSunekos
Not For Me
No member score yet
“I tried Sunekos 1200, and it gave me a fresh, healthy glow. I did like the result. The issue is that it felt similar to PDRN for me: temporary, expensive, and not something I need to keep repeating when my skincare is already strong. At around AED 3,600, I would rather invest in long-term skincare habits than keep paying for injectable glow.”
For: Fine Lines & Wrinkles · Dehydrated Skin · Loss of Firmness & Elasticity
TreatmentEvidence: A — Strong RCT evidence
✓ Editor triedSuperficial Peel
Worth Exploring
No member score yet
“I would start off with AHA/BHA peeling pads rather than a full blown chemical peel. There is a learning curve to exfoliation, on how to avoid damage to your skin barrier. Be gentle.”
For: PIH (Post-Inflammatory Hyperpigmentation) · Dullness & Uneven Tone · Rough Skin Texture
TreatmentEvidence: A — Strong RCT evidence
✓ Editor triedUltherapy
Love It
No member score yet
“I did Ultherapy around 2024 on my full face and neck, but not the cheeks/mid-face in a way that would risk unnecessary fat loss. I wanted lifting and to soften the saggy look after weight loss. I did see results, but this is not surgery and you should not expect a facelift. I do like it and would repeat it. My serious warning is fat loss: if the wrong person does it or the settings are wrong, losing facial fat is not something you can properly undo, even with fat grafting later. This is not a treatment to save money on.”
For: Loss of Firmness & Elasticity · Neck & Décolleté Aging · Crepey & Thinning Skin
TreatmentEvidence: A — Strong RCT evidence
✓ Editor triedThermage
Not For Me
No member score yet
“I tried Thermage in March 2025 while traveling, on my belly, because I had a little crepey skin there. It was extremely painful, and I usually have a good pain threshold. I did one session because that is the usual format, but I did not see much result. For that level of pain and cost, I would not do it again.”
For: Loss of Firmness & Elasticity · Crepey & Thinning Skin · Fine Lines & Wrinkles
TreatmentEvidence: C — Emerging evidence
✓ Editor triedEndolift
Approach With Caution
No member score yet
“Endolift is the treatment I have PTSD from. I did it on my face, neck, belly and back, and I spent a lot of money on it. On the body, I did not see a lasting difference; the immediate change felt like my body reacting to the trauma, not a real result. On my face, it harmed me. I had nerve damage near one side of my lower lip/corner area. Most of it recovered, thankfully, but not fully; I can still see unevenness when I stretch or make certain faces. Even with a good practitioner, a slight movement of the hand can create damage you may not fully recover from. I do not think this is worth the risk.”
For: Loss of Firmness & Elasticity · Facial Volume Loss · Neck & Décolleté Aging
TreatmentEvidence: B — Moderate evidence
✓ Editor triedPDRN / Polynucleotides
Worth Exploring
No member score yet
“I tried Rejuran in January 2026, mainly for my under-eyes. I had some product left, so my injector used the rest across my face and neck for glow. It did help my under-eye area and it did give that freshened-up skin look. But at AED 3,000 to 3,600, I did not feel the difference was big enough or long-lasting enough to justify doing it every few months. If your skin quality is already strong, the result may be nice but not dramatic. I would repeat it only if I really felt I needed it.”
For: Dark Circles & Under-Eye · Fine Lines & Wrinkles · Crepey & Thinning Skin
TreatmentEvidence: B — Moderate evidence
✓ Editor triedQ-Switch / Pico Laser
Not For Me
No member score yet
“I did Pico some time back, it didn make a different however not to the level of chemical peel or Clear and Brilliant level. My skin care regimen in general helps keep PIH at bay. But if I have to do it again, this wouldn't be my first choice.”
For: PIH (Post-Inflammatory Hyperpigmentation) · Melasma · Sun Damage & Dark Spots
TreatmentEvidence: A — Strong RCT evidence
✓ Editor triedBotox / Neuromodulators
Love It
No member score yet
“I use Dysport across my full face and platysmal bands, and I started in March 2025. For me, it has been a game changer - not because it makes me look different, but because my face looks fresher and my neck looks cleaner when the movement is softened. I weight train, and I metabolize it quickly, so movement comes back around the two-month mark. I still limit myself to about three sessions a year because I do not want to overdo it, build resistance, or let the muscles completely switch off. I tried masseter once and liked the slimming, but it created a little jowling for me, so I did not repeat it. I also tried a tiny lip flip and it looked too artificial for my face.”
For: Fine Lines & Wrinkles · Neck & Décolleté Aging
TreatmentEvidence: A — Strong RCT evidence
✓ Editor triedRadiesse
Love It
No member score yet
“I did hyperdiluted Radiesse on my whole face and neck. I wanted structural support and biostimulation, but I did not want added volume because I am cautious about future surgical options. It was subtle; this is not the treatment where you walk out looking lifted instantly. I saw it more around the two-to-six-week mark. What I liked is that it gave me a fresher, slightly more lifted look without making my face bigger. I also felt more comfortable with it than Sculptra because I am more concerned about Sculptra nodules. I would repeat Radiesse, but I would expect subtle improvement unless doing a proper course.”
For: Facial Volume Loss · Loss of Firmness & Elasticity · Fine Lines & Wrinkles
TreatmentEvidence: C — Emerging evidence
✓ Editor triedMicrodermabrasion
Not For Me
No member score yet
“I think I did microdermabrasion twice in forever. It gave some glow and helped dullness, but it was not a game changer and not something I cared to keep doing. If someone wants a treatment that actually changes superficial pigmentation and skin quality for me, I would choose regular microneedling instead.”
For: Rough Skin Texture · Dullness & Uneven Tone · Enlarged Pores
IngredientEvidence: D — Limited / anecdotal
Colloidal Gold
Not For Me
No member score yet
“I haven't tried this, and the evidence is genuinely limited - mostly anecdotal, not the kind of data that would move me to test it. This is an evidence call, not a dismissal for the sake of it.”
For: Fine Lines & Wrinkles
IngredientEvidence: C — Emerging evidence
CBD / Cannabidiol (Skincare)
Not For Me
No member score yet
“I haven't tried CBD skincare. Between the evidence still being emerging and the regulatory/product-quality inconsistency in this category (dosing and actual CBD content vary a lot between brands), it's not one I'm choosing to add.”
For: Acne (Comedonal & Cystic) · Rosacea & Redness · Damaged Skin Barrier
IngredientEvidence: C — Emerging evidence
Crystal-Infused Skincare
Not For Me
No member score yet
“I haven't tried crystal-infused products. There isn't a plausible skincare mechanism behind the crystal itself (any benefit would come from the base formula, not the crystals), so this isn't one I'm planning to test.”
IngredientEvidence: B — Moderate evidence
EGF, Growth Factors & Mimetics
Approach With Caution
No member score yet
No personal note logged yet — see the full research and evidence breakdown on the detail page.
For: Acne (Comedonal & Cystic) · Acne Scarring & Pitting · Fine Lines & Wrinkles
IngredientEvidence: B — Moderate evidence
Licorice Root Extract
Not For Me
No member score yet
“I haven't tried licorice root extract on its own. My hesitation isn't the evidence, which is moderate - it's standardisation: extract strength and actual glabridin content vary a lot between products, which makes it hard to know what you're really getting.”
For: PIH (Post-Inflammatory Hyperpigmentation) · Melasma · Rosacea & Redness
IngredientEvidence: C — Emerging evidence
Exosomes
Approach With Caution
No member score yet
No personal note logged yet — see the full research and evidence breakdown on the detail page.
For: Acne (Comedonal & Cystic) · Acne Scarring & Pitting · Fine Lines & Wrinkles
IngredientEvidence: C — Emerging evidence
Oxygen-Infused Skincare
Not For Me
No member score yet
“I haven't tried topical oxygen-infused products. The evidence for skin actually absorbing and using topical oxygen this way is thin, so it's not something I've chosen to add to my routine.”
IngredientEvidence: D — Limited / anecdotal
Plant Stem Cells
Not For Me
No member score yet
“I haven't tried plant stem cell skincare. The marketing outpaces the science here - plant cells don't become human skin cells, whatever the claims imply - so I'm sticking with antioxidant ingredients that have clearer, better-supported mechanisms.”
For: Fine Lines & Wrinkles
IngredientEvidence: C — Emerging evidence
Polyglutamic Acid (PGA)
Not For Me
No member score yet
“I haven't tried standalone PGA, and I'm not planning to yet - the products I've checked don't clearly verify meaningful PGA content (see the product note above), so there isn't one I trust enough to test.”
For: Damaged Skin Barrier · Dehydrated Skin
IngredientEvidence: C — Emerging evidence
Beta-Glucan
Not For Me
No member score yet
“I haven't tried beta-glucan. The evidence itself isn't weak - it's a reasonable soothing ingredient - I just don't have a gap in my routine it would fill better than what I'm already using. "Not For Me" is about my routine, not a verdict on the ingredient's evidence.”
For: Damaged Skin Barrier · Rosacea & Redness · Dehydrated Skin
IngredientEvidence: C — Emerging evidence
Postbiotics & Fermented Ingredients
Not For Me
No member score yet
“I haven't tried postbiotic/fermented skincare specifically. This category is very heterogeneous - results depend heavily on the exact strain and finished formula, not just the ingredient name - so I'm not confident enough in any single product yet to add one.”
For: Acne (Comedonal & Cystic) · Damaged Skin Barrier · Rosacea & Redness
IngredientEvidence: C — Emerging evidence
Squalane
Not For Me
No member score yet
“I haven't tried squalane specifically, and I'm not planning to - the evidence here is emerging rather than strong, and I already have emollients in my routine doing this job well. "Not For Me" here means "not worth swapping in," not "doesn't work."”
For: Damaged Skin Barrier · Dehydrated Skin
IngredientEvidence: B — Moderate evidence
Ectoin
Worth Exploring
No member score yet
No personal note logged yet — see the full research and evidence breakdown on the detail page.
For: Sun Damage & Dark Spots · Damaged Skin Barrier · Rosacea & Redness
IngredientEvidence: C — Emerging evidence
Volufiline (Sarsasapogenin)
Worth Exploring
No member score yet
No personal note logged yet — see the full research and evidence breakdown on the detail page.
For: Fine Lines & Wrinkles · Facial Volume Loss · Neck & Décolleté Aging
TreatmentEvidence: B — Moderate evidence
Fractional CO2 Laser
Worth Exploring
No member score yet
“Moxie has not tried fractional CO2 yet. She sees it as one of the big guns: effective, serious, and not something to do casually. She may consider it one day for under-eye crepey skin, but only with extreme caution because downtime, aftercare and skin-tone risk matter.”
For: Acne Scarring & Pitting · Rough Skin Texture · Fine Lines & Wrinkles
TreatmentEvidence: B — Moderate evidence
IPL / Intense Pulsed Light
Not For Me
No member score yet
“Moxie has not tried IPL and does not see it as a treatment for her personally.”
For: Rosacea & Redness · Sun Damage & Dark Spots · Dullness & Uneven Tone
TreatmentEvidence: C — Emerging evidence
Onda Coolwaves
Not For Me
No member score yet
“Moxie has not tried Onda Coolwaves and says it is not for her.”
TreatmentEvidence: B — Moderate evidence
Cosmelan Peel
Not For Me
No member score yet
“I have not personally done Cosmelan, but I made my mother do it once. It helped her melasma and uneven skin tone, but the downtime was tough - about 10 days. My issue is that if you have sensitive skin or even a little sun exposure, melasma can come back. This does not replace skincare. Personally, I would rather use gentler peels or peel pads more consistently, strict sunscreen and pigmentation-focused ingredients.”
For: PIH (Post-Inflammatory Hyperpigmentation) · Melasma · Sun Damage & Dark Spots
TreatmentEvidence: C — Emerging evidence
HIFU (Generic / Non-Branded Devices)
Approach With Caution
No member score yet
“I haven't personally done a generic or unbranded HIFU treatment — my documented experience is specifically with Ultherapy, the branded FDA-cleared version, which has its own page. I'm including this page because "HIFU" gets marketed so broadly that it's easy to book a treatment thinking you're getting Ultherapy-level technology and evidence when you're not. If a clinic says "HIFU" without naming the actual device, ask. The fat-loss risk I warn about on the Ultherapy page applies here too, arguably more so without real-time imaging to guide depth.”
For: Loss of Firmness & Elasticity · Neck & Décolleté Aging · Crepey & Thinning Skin
TreatmentEvidence: B — Moderate evidence
Nd:YAG Vascular Laser
Worth Exploring
No member score yet
“Moxie has not personally tried Nd:YAG vascular laser.”
For: Rosacea & Redness
TreatmentEvidence: A — Strong RCT evidence
Sculptra
Approach With Caution
No member score yet
“Moxie has not personally tried Sculptra. Her reason is simple: she does not want more facial volume, she is cautious about nodules, and she is thinking long-term about future procedures. This is not something she would do cheaply or casually. If someone truly wants collagen-based volume, it may be worth exploring, but only with a highly experienced injector and a clear understanding that it is not reversible like HA filler.”
For: Facial Volume Loss · Loss of Firmness & Elasticity · Crepey & Thinning Skin
TreatmentEvidence: D — Limited / anecdotal
Oxygen Facial
Approach With Caution
No member score yet
“Moxie has not personally tried an oxygen facial.”
For: Dehydrated Skin · Dullness & Uneven Tone
TreatmentEvidence: C — Emerging evidence
Volnewmer
Worth Exploring
No member score yet
“Moxie has not tried Volnewmer yet. It was recommended by an injector whose opinion she trusts, as something to explore before choosing more aggressive energy devices or collagen injectables.”
For: Fine Lines & Wrinkles · Loss of Firmness & Elasticity
TreatmentEvidence: B — Moderate evidence
Profhilo
Worth Exploring
No member score yet
No personal note logged yet — see the full research and evidence breakdown on the detail page.
For: Crepey & Thinning Skin · Loss of Firmness & Elasticity · Dehydrated Skin
TreatmentEvidence: A — Strong RCT evidence
TCA Peel
Worth Exploring
No member score yet
“Moxie has not personally tried a TCA medium-depth peel, this is not something to attempt at home. Medium-depth TCA requires a qualified professional to control concentration, layering and depth; DIY versions risk scarring and burns.”
For: Acne Scarring & Pitting · PIH (Post-Inflammatory Hyperpigmentation) · Fine Lines & Wrinkles
TreatmentEvidence: C — Emerging evidence
Moxi Laser
Worth Exploring
No member score yet
“Moxie has not personally tried Moxi yet. She has seen promising research and user before-and-afters, and many people seem to swear by it, especially when combined with BBL. Her caution is straightforward: find someone who can assess your skin type and actual concern, not just sell the device.”
For: Dullness & Uneven Tone · PIH (Post-Inflammatory Hyperpigmentation) · Fine Lines & Wrinkles
TreatmentEvidence: C — Emerging evidence
Stem Cell Therapy
Worth Exploring
No member score yet
“Moxie has not personally tried aesthetic stem cell therapy. She considers it worth exploring as a category, but only with emerging-evidence caution and exact product verification.”
For: Acne Scarring & Pitting · Loss of Firmness & Elasticity · Fine Lines & Wrinkles
TreatmentEvidence: D — Limited / anecdotal
Xerf
Worth Exploring
No member score yet
“Moxie has not tried XERF yet, but considers it worth exploring based on the published mechanism. This is not personal experience, verify the exact device and protocol details with your clinic before booking.”
For: Loss of Firmness & Elasticity · Fine Lines & Wrinkles · Crepey & Thinning Skin
TreatmentEvidence: C — Emerging evidence
PDO Thread Lift
Not For Me
No member score yet
“This is something I would never do. A thread lift is temporary, and yes, it can give lift, but you are putting barbed threads under the skin to pull tissue. I do not like the risk-to-reward ratio. It can create unevenness, internal scarring and problems later. You can research this and find people with bad experiences that took a long time to recover, if they recovered fully. Even with a good doctor, this is not for me and not something I would recommend.”
For: Loss of Firmness & Elasticity · Facial Volume Loss · Neck & Décolleté Aging
TreatmentEvidence: B — Moderate evidence
Erbium Laser
Worth Exploring
No member score yet
“Moxie has not personally tried erbium laser.”
For: Acne Scarring & Pitting · Rough Skin Texture · Fine Lines & Wrinkles
TreatmentEvidence: C — Emerging evidence
Carbon Laser Peel
Not For Me
No member score yet
“Moxie has not personally tried carbon laser peel.”
For: Enlarged Pores · Acne (Comedonal & Cystic) · Dullness & Uneven Tone
TreatmentEvidence: B — Moderate evidence
BBL / BroadBand Light
Worth Exploring
No member score yet
“Moxie has not personally tried BBL. She sees it as worth exploring for dullness, pigmentation and sunspots, especially because it is often quick and relatively gentle compared with bigger resurfacing treatments. Her caveat is firm: none of these treatments replaces sunscreen, skincare and pigmentation-focused ingredients. If the daily routine is weak, the pigment can come back.”
For: Sun Damage & Dark Spots · Dullness & Uneven Tone · Rosacea & Redness